A RADICAL INTERPRETATION OF IMMUNITY TO MALARIA PARASITES
作者： AnthonyC Allison , ElsieM Eugui
DOI: 10.1016/S0140-6736(82)91330-7
关键词:
摘要: Abstract Asexual forms of malaria parasites in erythrocytes are sensitive to oxidant stress. Immunity these is thymus-dependent and may be mediated by the binding effector cells (macrophages or natural killer cells) surface parasitised cells, with concomitant production superoxide anion (OF). This can lead degeneration erythrocytes. Antibodies facilitate erythrocytes, reinforcing effects cell-mediated immunity. Plasmodium falciparum more stress human abnormal haemoglobins glucose-6-phosphate-dehydrogenase deficiency than normal Thus immune responses, producing stress, could act synergistically inherited traits increase chances survival children during dangerous years first exposure malaria.
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