Indoloditerpenes from an algicolous isolate of Aspergillus oryzae.

作者: Ming-Feng Qiao , Nai-Yun Ji , Xiang-Hong Liu , Ke Li , Qing-Mei Zhu

DOI: 10.1016/J.BMCL.2010.08.024

关键词:

摘要: Two new indoloditerpene derivatives asporyzin A (1) and B (2), one C (3), three known related indoloditerpenes JBIR-03 (4), emindole SB (5), emeniveol (6) were isolated from an endophytic fungus Aspergillus oryzae, the marine red alga Heterosiphonia japonica. Their structures unambiguously established by spectroscopic techniques. In addition, all isolates evaluated preliminarily for insecticidal antimicrobial activities in order to probe into their chemical defensive function. Compound 4 was more active against brine shrimp than others, 3 possessed potent activity Escherichia coli.

参考文章(14)
P. G. Mantle, S. J. Burt, K. M. Macgeorge, J. N. Bilton, R. N. Sheppard, Oxidative transformation of paxilline in sheep bile. Xenobiotica. ,vol. 20, pp. 809- 821 ,(1990) , 10.3109/00498259009046895
Koohei Nozawa, Shoichi Nakajima, Ken-ichi Kawai, Shun-ichi Udagawa, Isolation and structures of indoloditerpenes, possible biosynthetic intermediates to the tremorgenic mycotoxin, paxilline, from Emericella striata Journal of The Chemical Society-perkin Transactions 1. ,vol. 9, pp. 2607- 2610 ,(1988) , 10.1039/P19880002607
Yasuo Kimura, Masahiko Nishibe, Hiromitsu Nakajima, Takashi Hamasaki, Norihiro Shigemitsu, Fumio Sugawara, Thomas J. Stout, Jon Clardy, Emeniveol; A new pollen growth inhibitor from the fungus, Emericella nivea Tetrahedron Letters. ,vol. 33, pp. 6987- 6990 ,(1992) , 10.1016/S0040-4039(00)60913-9
Akemi Umeyama, Miharu Nozaki, Shigenobu Arihara, Polasols A−C, Three New Diterpenes from the Marine Sponge Epipolasis sp. Journal of Natural Products. ,vol. 61, pp. 945- 947 ,(1998) , 10.1021/NP9705625
Masahiro Ogata, Jun-ya Ueda, Midori Hoshi, Junko Hashimoto, Takuji Nakashima, Kozue Anzai, Motoki Takagi, Kazuo Shin-ya, A novel indole-diterpenoid, JBIR-03 with anti-MRSA activity from Dichotomomyces cejpii var. cejpii NBRC 103559. The Journal of Antibiotics. ,vol. 60, pp. 645- 648 ,(2007) , 10.1038/JA.2007.83
Pablo Solis, Colin Wright, Margaret Anderson, Mahabir Gupta, J. Phillipson, A microwell cytotoxicity assay using Artemia salina (brine shrimp). Planta Medica. ,vol. 59, pp. 250- 252 ,(1993) , 10.1055/S-2006-959661
Susana López, Jaume Bastida, Francesc Viladomat, Carles Codina, Acetylcholinesterase inhibitory activity of some Amaryllidaceae alkaloids and Narcissus extracts. Life Sciences. ,vol. 71, pp. 2521- 2529 ,(2002) , 10.1016/S0024-3205(02)02034-9
John G. Ondeyka, Gregory L. Helms, Otto D. Hensens, Michael A. Goetz, Deborah L. Zink, Athanasios Tsipouras, Wesley L. Shoop, Lyndia Slayton, Anne W. Dombrowski, Jon D. Polishook, Dan A. Ostlind, Nancy N. Tsou, Richard G. Ball, Sheo B. Singh, Nodulisporic Acid A, a Novel and Potent Insecticide from a Nodulisporium Sp. Isolation, Structure Determination, and Chemical Transformations Journal of the American Chemical Society. ,vol. 119, pp. 8809- 8816 ,(1997) , 10.1021/JA971664K
Otto D. Hensens, John G. Ondeyka, Anne W. Dombrowski, Dan A. Ostlind, Deborah L. Zink, Isolation and structure of nodulisporic acid A1 and A2, novel insecticides from a Nodulisporium sp. Tetrahedron Letters. ,vol. 40, pp. 5455- 5458 ,(1999) , 10.1016/S0040-4039(99)01064-3
Manuel Norte, Jose´J. Ferna´ndez, Agusti´n Padilla, Bisabolane halogenated sesquiterpenes fromLaurencia Phytochemistry. ,vol. 31, pp. 326- 327 ,(1992) , 10.1016/0031-9422(91)83065-S