Nickel-catalyzed denitrogenative annulation reactions of 1,2,3-benzotriazin-4(3H)-ones with 1,3-dienes and alkenes.

摘要: 1,2,3-Benzotriazin-4(3H)-ones react with 1,3-dienes in the presence of a nickel(0)/phosphine complex to give variety 3,4-dihydroisoquinolin-1(2H)-ones. Oxidative insertion nickel(0) into triazinone moiety prompts extrusion dinitrogen five-membered ring azanickelacyclic intermediate. Subsequent nickel−carbon bond followed by allylic amidation affords Alkenes also undergo intermediate, and subsequent reductive elimination gives 3-substituted