Transdermal Fentanyl for Cancer Pain Repeated Dose Pharmacokinetics

作者： Russell K. Portenoy , Mary A. Southam , Suneel K. Gupta , Jeanne Lapin , Mary Layman

DOI: 10.1097/00000542-199301000-00007

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摘要: BackgroundThe transdermal therapeutic system (fentanyl), or TTS(fentanyl), continuously delivers fentanyl for up to 72 h. The (fentanyl)-lOO approximately 100 μg/h. repeated dose pharmacokinetics of this drug using the recommended dosing interval have not