Putative plasmid prophages of Bacillus cereus sensu lato may hold the key to undiscovered phage diversity

作者: Andrey M Shadrin , Nikita A Nikulin , Emma G Piligrimova , Olesya A Kazantseva , Anna V Skorynina

DOI: 10.1038/S41598-021-87111-3

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摘要: Bacteriophages are bacterial viruses and the most abundant biological entities on Earth. Temperate bacteriophages can form prophages stably maintained in host population: they either integrate into genome or replicate as plasmids cytoplasm. As shown, tailed temperate may circular plasmid many species of taxa Firmicutes, Gammaproteobacteria Spirochaetes. The actual number such is thought to be underestimated for two main reasons: first, whole genome-sequencing assemblies, difficult distinguish from plasmids; second, there an absence experimental studies which vital confirm their existence. In appear especially numerous. present study, we identified 23 genomes Bacillus cereus group that were deposited GenBank belong with little no homology known viruses. We consider these putative worth assays since it will broaden our knowledge phage diversity suggest more attention paid molecules all sequencing projects this help identifying previously unknown phages.

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