Lymphokines in the rheumatoid joint.

作者: Peter Stastny , Moshe Rosenthal , Mario Andreis , Morris Ziff

DOI: 10.1002/ART.1780180307

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摘要: Joint fluids and culture supernatants of synovial tissue were examined for the presence two lymphokines. Migration inhibitory activity was found in 16 22 rheumatoid (73%), 3 15 osteoarthritis (20%), 11 from patients with various inflammatory arthritides (27%). Blastogenic present 14 1 7 nonrheumatoid effusions. The active materials eluted third peak Sephadex G-200 therefore smaller than immunoglobulin or immune complexes. These findings suggest that lymphokine-like substances effusions most arthritis some other forms chronic synovitis.

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