How is Helicobacter pylori transmitted

作者: David R. Cave

DOI: 10.1016/S0016-5085(97)80004-2

关键词:

摘要: Helicobacter pylori is one of the world's most common pathogens. It colonizes about 60% population, causes gastritis and peptic ulcer, strongly associated with gastric adenocarcinoma lymphoma. However, individuals never develop clinical disease. Thirteen years after culture H. by Marshall Warren, we still do not know its major mode transmission. Childhood represents period acquisition infection in third world, but rare children developed world. Possible routes include either oral-oral or fecal-oral, iatrogenic spread inadvertent use unsterile pH probes endoscopes, vectorial flies. Evidence to support each route transmission provided, there no predominant route. The only significant reservoir appears be humans themselves. organism has been found some domestic cats nonhuman primates, opportunities for human interaction latter are rare, making from this source an unlikely possibility. propensity become a coccoid form. This may represent persistent form which can exist environment, it yet shown that revert replicative

参考文章(43)
H. M. Mitchell, Y. Y. Li, P. J. Hu, Q. Liu, M. Chen, G. G. Du, Z. J. Wang, A. Lee, S. L. Hazell, Epidemiology of Helicobacter pylori in southern China: identification of early childhood as the critical period for acquisition. The Journal of Infectious Diseases. ,vol. 166, pp. 149- 153 ,(1992) , 10.1093/INFDIS/166.1.149
D Cohen, M Green, C Block, R Slepon, R Ambar, S.S Wasserman, M.M Levine, REDUCTION OF TRANSMISSION OF SHIGELLOSIS BY CONTROL OF HOUSEFLIES (MUSCA DOMESTICA) The Lancet. ,vol. 337, pp. 993- 997 ,(1991) , 10.1016/0140-6736(91)92657-N
A. T. R. AXON, Review article Is Helicobacter pylori transmitted by the gastro‐oral route? Alimentary Pharmacology & Therapeutics. ,vol. 9, pp. 585- 588 ,(2007) , 10.1111/J.1365-2036.1995.TB00426.X
Blaine R. Miller, James A. Tharp, W.Bradford Issacs, Gastric residual volume in infants and children following a 3-hour fast. Journal of Clinical Anesthesia. ,vol. 2, pp. 301- 305 ,(1990) , 10.1016/0952-8180(90)90074-D
Luigina Cellini, Nerino Allocati, Domenico Angelucci, Teresa Iezzi, Emanuela Di Campli, Leonardo Marzio, Benedetto Dainelli, Coccoid Helicobacter pylori Not Culturable In Vitro Reverts in Mice Microbiology and Immunology. ,vol. 38, pp. 843- 850 ,(1994) , 10.1111/J.1348-0421.1994.TB02136.X
L.H.H. Cheng, M. Webberley, M. Evans, N. Hanson, R. Brown, Helicobacter pylori in dental plaque and gastric mucosa Oral Surgery Oral Medicine Oral Pathology Oral Radiology and Endodontology. ,vol. 81, pp. 421- 423 ,(1996) , 10.1016/S1079-2104(96)80017-5
Pär Aleljung, Hans-Olof Nilsson, Xin Wang, Patrik Nyberg, Torsten Mörner, Ibrahim Warsame, Torkel Wadström, Gastrointestinal colonisation of BALB/cA mice byHelicobacter pylorimonitored by heparin magnetic separation FEMS Immunology & Medical Microbiology. ,vol. 13, pp. 303- 309 ,(1996) , 10.1111/J.1574-695X.1996.TB00255.X
P.D. Klein, A.R. Opekun, E.O. Smith, P.D. Klein, D.Y. Graham, D.Y. Graham, A. Gaillour, Gastrointestinal Physiology Working Group, Water source as risk factor for Helicobacter pylori infection in Peruvian children The Lancet. ,vol. 337, pp. 1503- 1506 ,(1991) , 10.1016/0140-6736(91)93196-G
J.E. Thomas, G.R. Gibson, M.K. Darboe, L.T. Weaver, A. Dale, Isolation of Helicobacter pylori from human faeces. The Lancet. ,vol. 340, pp. 1194- 1195 ,(1992) , 10.1016/0140-6736(92)92894-L
Robert J. Hopkins, Pablo A. Vial, Catterine Ferreccio, Jimena Ovalle, Priscilla Prado, Viviana Sotomayor, Robert G. Russell, Steven S. Wasserman, J. Glenn Morris, Seroprevalence of Helicobacter pylori in Chile: Vegetables May Serve as One Route of Transmission The Journal of Infectious Diseases. ,vol. 168, pp. 222- 226 ,(1993) , 10.1093/INFDIS/168.1.222