Water-extract of Helianthus annuus Seed Exhibits Potent Anti-asthma Activity In Vitro and In Vivo

摘要: In order to investigate whether antioxidant biomaterials inhibits IL-4 and/or IL-13 expression in vitro and vivo, we carried out assays by enzyme or cell-based with Helianthus annuus extract. Antioxidant include DPPH, FRAP, hydroxyl radical assays. extract exhibited SOD scavenging activity, had different patterns each solvent extracted reaction. DW inhibited oxidative stress that induced apoptosis. We measured cell IL-/13 cytokine a classical mouse animal model. The result show showed strung inhibition of immune response the lung. These suggest can reduce inflammation n asthma