Renillenoic acids: Feeding deterrence and antifouling properties of conjugated fatty acids in Patagonian sea pen

摘要: Abstract Chemical studies in the octocoral Renilla octodentata from San Jorge Gulf (Patagonia, Argentina) have been carried out for first time. Two conjugated polyunsaturated fatty acids, 1 and 2 , named renillenoic acids (RAs), were isolated characterized sea pen. These compounds, analogs of eicosapentaenoic acid (EPA) arachidonic (AA), accounted a large fraction (20%) organic extract octocoral. Renillenoic uniform distributed rachis peduncle showed comparable volumetric concentrations, 1.61 ± 0.51 mg/cm 3 2.00 ± 1.01 mg/cm respectively (Paired Student's  t -test, two tailed, p > 0.05). Below physiological extracts (28.20 mg/g), tissue sclerites (0.66 ± 0.02 g/g) feeding deterrence against generalist fish Pagrus pagrus (Fisher exact test, one p  Amphibalanus amphitrite revealed anti-settlement activity (acetone extract = 1.49 mg/L, diethyl ether extract = 3.16 mg/L). active cypris larvae (EC 50  = 4.09 mg/L) favorably low toxicities nauplii cyprids (LC over 100 mg/L). The results suggest that chemical physical defense R. operate additively or synergistically to protect sessile organisms predators biofoulers.