The contribution of culturomics to the repertoire of isolated human bacterial and archaeal species.

摘要: After a decade of research and metagenomic analyses, our knowledge the human microbiota appears to have reached plateau despite promising results. In many studies, culture has proven be essential in describing new prokaryotic species filling gaps. 2015, only 2172 different were reported been isolated at least once from body as pathogens or commensals. this review, we update previous repertoire by reporting date, increasing it 28% reach total 2776 associated with beings. They classified into 11 phyla, mostly Firmicutes, Proteobacteria, Bacteroidetes, Actinobacteria. Finally, culturomics contributed up 66.2% towards updating 400 species, which 288 novel. This demonstrates need continue culturing work, seems order decipher hidden microbial content.