Diversity and evolution of secondary metabolism in the marine actinomycete genus Salinispora

作者: N. Ziemert , A. Lechner , M. Wietz , N. Millan-Aguinaga , K. L. Chavarria

DOI: 10.1073/PNAS.1324161111

关键词:

摘要: … as false positives (N-acetyltransferases) and the remaining 1,924 (92.5%) were associated with secondary metabolism. All of the C domains were linked to secondary metabolism. …

参考文章(66)
Nadine Ziemert, Paul R. Jensen, Phylogenetic Approaches to Natural Product Structure Prediction Methods in Enzymology. ,vol. 517, pp. 161- 182 ,(2012) , 10.1016/B978-0-12-404634-4.00008-5
Kelle C. Freel, Anna Edlund, Paul R. Jensen, Microdiversity and evidence for high dispersal rates in the marine actinomycete 'Salinispora pacifica'. Environmental Microbiology. ,vol. 14, pp. 480- 493 ,(2012) , 10.1111/J.1462-2920.2011.02641.X
Lina Ahmed, Paul R. Jensen, Kelle C. Freel, Ros Brown, Amanda L. Jones, Byung-Yong Kim, Michael Goodfellow, Salinispora pacifica sp. nov., an actinomycete from marine sediments Antonie Van Leeuwenhoek International Journal of General and Molecular Microbiology. ,vol. 103, pp. 1069- 1078 ,(2013) , 10.1007/S10482-013-9886-4
Ulrich Dobrindt, Bianca Hochhut, Ute Hentschel, Jörg Hacker, Genomic islands in pathogenic and environmental microorganisms Nature Reviews Microbiology. ,vol. 2, pp. 414- 424 ,(2004) , 10.1038/NRMICRO884
Nadine Ziemert, Sheila Podell, Kevin Penn, Jonathan H. Badger, Eric Allen, Paul R. Jensen, The Natural Product Domain Seeker NaPDoS: A Phylogeny Based Bioinformatic Tool to Classify Secondary Metabolite Gene Diversity PLoS ONE. ,vol. 7, pp. e34064- ,(2012) , 10.1371/JOURNAL.PONE.0034064
D. W. Udwary, L. Zeigler, R. N. Asolkar, V. Singan, A. Lapidus, W. Fenical, P. R. Jensen, B. S. Moore, Genome sequencing reveals complex secondary metabolome in the marine actinomycete Salinispora tropica Proceedings of the National Academy of Sciences of the United States of America. ,vol. 104, pp. 10376- 10381 ,(2007) , 10.1073/PNAS.0700962104
Xidong Feng, Margaret Leighton, Frank E. Koehn, Bradley S. Moore, Akimasa Miyanaga, Jeffrey E. Janso, Leonard McDonald, Min He, Hongbo Liu, Laurel Barbieri, Alessandra S. Eustáquio, Elisha N. Fielding, Guy T. Carter, Paul R. Jensen, Discovery and Assembly-Line Biosynthesis of the Lymphostin Pyrroloquinoline Alkaloid Family of mTOR Inhibitors in Salinispora Bacteria Journal of the American Chemical Society. ,vol. 133, pp. 13311- 13313 ,(2011) , 10.1021/JA205655W
Holger Jenke-Kodama, Elke Dittmann, Evolution of metabolic diversity: insights from microbial polyketide synthases. Phytochemistry. ,vol. 70, pp. 1858- 1866 ,(2009) , 10.1016/J.PHYTOCHEM.2009.05.021
Holger Jenke-Kodama, Elke Dittmann, Bioinformatic perspectives on NRPS/PKS megasynthases: advances and challenges. Natural Product Reports. ,vol. 26, pp. 874- 883 ,(2009) , 10.1039/B810283J