DNA Repair: ERCC1, Nucleotide Excision Repair, and Platinum Resistance
作者： Eddie Reed , Teri L. Larkins , Cindy H. Chau , William D. Figg
DOI: 10.1007/978-1-4614-9135-4_18
关键词:
摘要: DNA excision repair plays a significant part in platinum-based chemotherapy by removing lesions caused platinum-containing drugs. The nucleotide (NER) pathway is the mammalian mechanism that removes bulky adducts induced damaging chemotherapeutic agents. Platinum compounds induce their cytotoxic effect binding to molecule form of platinum-DNA-adduct. NER main responsible for platinum resistance increased platinum-DNA-adduct removal and cross complementing-group 1 (ERCC1) gene major role NER-pathway because its damage recognition ability. This chapter will review mechanisms as it relates regulation ERCC1. A brief discussion on cancer stem cells also presented.
springer.com
sci-hub.se 参考文章(92)
Yu Jj, Reed E, Li Q, Yunmbam Mk, Slavsky D, Cross Cl, Bostick-Bruton F, Mu C, Association between the level of ERCC-1 expression and the repair of cisplatin-induced DNA damage in human ovarian cancer cells. Anticancer Research. ,vol. 20, pp. 645- 652 ,(2000)
M D Dabholkar, R J Parker, K B Lee, E Reed, F Bostick-Bruton, Taxol effect on cisplatin sensitivity and cisplatin cellular accumulation in human ovarian cancer cells. Journal of The National Cancer Institute Monographs. pp. 83- 88 ,(1993)
Manasses K. Yunmbam, Jing Jie Yu, Eddie Reed, Xiaosong Zhong, Len Neckers, Edward G. Mimnaugh, Qingdi Q. Li, Lactacystin enhances cisplatin sensitivity in resistant human ovarian cancer cell lines via inhibition of DNA repair and ERCC-1 expression. Cellular and Molecular Biology. ,vol. 47, ,(2001)
Wilma M. McKoy, Karen R. Grotzinger, Timothy J. Kinsella, Karen G. Louie, Robert F. Ozols, Margaret A. Winker, Brent C. Behrens, Thomas C. Hamilton, Radiation Survival Parameters of Antineoplastic Drug-sensitive and -resistant Human Ovarian Cancer Cell Lines and Their Modification by Buthionine Sulfoximine Cancer Research. ,vol. 45, pp. 2110- 2115 ,(1985)
J C Jones, W P Zhen, E Reed, R J Parker, A Sancar, V A Bohr, Gene-specific formation and repair of cisplatin intrastrand adducts and interstrand cross-links in Chinese hamster ovary cells. Journal of Biological Chemistry. ,vol. 266, pp. 7101- 7107 ,(1991) , 10.1016/S0021-9258(20)89616-1
Charles Egwuagu, Justine A. Vionnet, Meenakshi D. Dabholkar, John R. Silber, Jing Jie Yu, Mitchel S. Berger, Eddie Reed, Malignant and nonmalignant brain tissues differ in their messenger RNA expression patterns for ERCC1 and ERCC2. Cancer Research. ,vol. 55, pp. 1261- 1266 ,(1995)
J.J. Lin, A Sancar, Active site of (A)BC excinuclease. I. Evidence for 5' incision by UvrC through a catalytic site involving Asp399, Asp438, Asp466, and His538 residues. Journal of Biological Chemistry. ,vol. 267, pp. 17688- 17692 ,(1992) , 10.1016/S0021-9258(19)37097-8
Steven A. Rosenberg, Vincent T. DeVita, Samuel Hellman, Cancer : Principles and Practice of Oncology ,(1982)
Kurt W. Kohn, Jonathan M. Ducore, Guy Laurent, Leonard C. Erickson, Leonard A. Zwelling, Comparative studies of DNA cross-linking and cytotoxicity in Burkitt's lymphoma cell lines treated with cis-diamminedichloroplatinum(II) and L-phenylalanine mustard. Cancer Research. ,vol. 42, pp. 897- 902 ,(1982)
Eddie Reed, Nucleotide excision repair and anti-cancer chemotherapy Cytotechnology. ,vol. 27, pp. 187- 201 ,(1998) , 10.1023/A:1008016922425