Sex hormones and hepatic neoplasia.

摘要: Reports regarding the recent increase in hepatocellular neoplasma women taking oral contraceptives and persons anabolic androgenic steroids are reviewed 6 additional cases reported. These tumors often quite large. They frequently undergo central hemorrhagic necrosis enlarging hematoma ruptures through capsule. Focal nuclear hyper plasia may be an incidental finding at autopsy. Only 1 carcinoma has been reported contraceptives. However of authors showed features suggestive a transition to that some areas severe dysplasia more atypia than usual benign adenoma. The presence crystals mitochondria cells this tumor were thought significant. carcinogenic or cocarcinogenic role synthetic steroid sex hormones not shown. showing marked decrease biliary excretion organic ions after intake increased risk for developing hepatic neoplasms. A simple test defective anions is needed. postparandial serum bile determination intravenous acid tolerance suggested.