Ethanol Enhances GABAergic Transmission Onto Dopamine Neurons in the Ventral Tegmental Area of the Rat

作者: Jonathan W. Theile , Hitoshi Morikawa , Reuben A. Gonzales , Richard A. Morrisett

DOI: 10.1111/J.1530-0277.2008.00665.X

关键词:

摘要: Background: Activation of the dopaminergic (DA) neurons of the ventral tegmental area (VTA) by ethanol has been implicated in its rewarding and reinforcing effects. At most central …

参考文章(39)
Zhiguo Nie, Paul Schweitzer, Amanda J Roberts, Samuel G Madamba, Scott D Moore, George Robert Siggins, Ethanol augments GABAergic transmission in the central amygdala via CRF1 receptors. Science. ,vol. 303, pp. 1512- 1514 ,(2004) , 10.1126/SCIENCE.1092550
Sarah B. Appel, William J. McBride, Marco Diana, Ivan Diamond, Antonello Bonci, Mark S. Brodie, Ethanol Effects on Dopaminergic “Reward” Neurons in the Ventral Tegmental Area and the Mesolimbic Pathway Alcoholism: Clinical and Experimental Research. ,vol. 28, pp. 1768- 1778 ,(2004) , 10.1097/01.ALC.0000145976.64413.21
M. Roberto, S. G. Madamba, S. D. Moore, M. K. Tallent, G. R. Siggins, Ethanol increases GABAergic transmission at both pre- and postsynaptic sites in rat central amygdala neurons Proceedings of the National Academy of Sciences of the United States of America. ,vol. 100, pp. 2053- 2058 ,(2003) , 10.1073/PNAS.0437926100
Mark S. Brodie, Sarah A. Shefner, Thomas V. Dunwiddie, Ethanol increases the firing rate of dopamine neurons of the rat ventral tegmental area in vitro. Brain Research. ,vol. 508, pp. 65- 69 ,(1990) , 10.1016/0006-8993(90)91118-Z
Cheng Xiao, Jingli Zhang, Krešimir Krnjević, Jiang Hong Ye, Effects of Ethanol on Midbrain Neurons: Role of Opioid Receptors Alcoholism: Clinical and Experimental Research. ,vol. 31, pp. 1106- 1113 ,(2007) , 10.1111/J.1530-0277.2007.00405.X
George F. Koob, Amanda J. Roberts, Gery Schulteis, Loren H. Parsons, Charles J. Heyser, Petri Hyytia, Emilio Merlo-Pich, Friedbert Weiss, Neurocircuitry targets in ethanol reward and dependence. Alcoholism: Clinical and Experimental Research. ,vol. 22, pp. 3- 9 ,(1998) , 10.1111/J.1530-0277.1998.TB03611.X
Mark S. Brodie, Sarah B. Appel, The Effects of Ethanol on Dopaminergic Neurons of the Ventral Tegmental Area Studied with Intracellular Recording in Brain Slices Alcoholism: Clinical and Experimental Research. ,vol. 22, pp. 236- 244 ,(1998) , 10.1111/J.1530-0277.1998.TB03644.X
George Robert Siggins, Marisa Roberto, Zhiguo Nie, The tipsy terminal: presynaptic effects of ethanol. Pharmacology & Therapeutics. ,vol. 107, pp. 80- 98 ,(2005) , 10.1016/J.PHARMTHERA.2005.01.006