A T cell-specific deletion of HDAC1 protects against experimental autoimmune encephalomyelitis

作者: Lisa Göschl , Teresa Preglej , Patricia Hamminger , Michael Bonelli , Liisa Andersen

DOI: 10.1016/J.JAUT.2017.09.008

关键词:

摘要: … Application of pan-histone deacetylase inhibitors (HDACi) ameliorates experimental autoimmune encephalomyelitis (EAE), an animal model for MS, suggesting that HDACi might be a …

参考文章(60)
Melanie Greter, Iva Lelios, Andrew Lewis Croxford, Microglia Versus Myeloid Cell Nomenclature during Brain Inflammation Frontiers in Immunology. ,vol. 6, pp. 249- 249 ,(2015) , 10.3389/FIMMU.2015.00249
Kiyoshi Hirahara, Atsushi Onodera, Alejandro V Villarino, Michael Bonelli, Giuseppe Sciumè, Arian Laurence, Hong-Wei Sun, Stephen R Brooks, Golnaz Vahedi, Han-Yu Shih, Gustavo Gutierrez-Cruz, Shigeru Iwata, Ryo Suzuki, Yohei Mikami, Yoshitaka Okamoto, Toshinori Nakayama, Steven M Holland, Christopher A Hunter, Yuka Kanno, John J O’Shea, Asymmetric Action of STAT Transcription Factors Drives Transcriptional Outputs and Cytokine Specificity. Immunity. ,vol. 42, pp. 877- 889 ,(2015) , 10.1016/J.IMMUNI.2015.04.014
Ervin E. Kara, Duncan R. McKenzie, Cameron R. Bastow, Carly E. Gregor, Kevin A. Fenix, Abiodun D. Ogunniyi, James C. Paton, Matthias Mack, Diana R. Pombal, Cyrill Seillet, Bénédicte Dubois, Adrian Liston, Kelli P. A. MacDonald, Gabrielle T. Belz, Mark J. Smyth, Geoffrey R. Hill, Iain Comerford, Shaun R. McColl, CCR2 defines in vivo development and homing of IL-23-driven GM-CSF-producing Th17 cells Nature Communications. ,vol. 6, pp. 8644- 8644 ,(2015) , 10.1038/NCOMMS9644
Reinhard Grausenburger, Ivan Bilic, Nicole Boucheron, Gordin Zupkovitz, Lamia El-Housseiny, Roland Tschismarov, Yu Zhang, Martina Rembold, Martin Gaisberger, Arnulf Hartl, Michelle M. Epstein, Patrick Matthias, Christian Seiser, Wilfried Ellmeier, Conditional Deletion of Histone Deacetylase 1 in T Cells Leads to Enhanced Airway Inflammation and Increased Th2 Cytokine Production Journal of Immunology. ,vol. 185, pp. 3489- 3497 ,(2010) , 10.4049/JIMMUNOL.0903610
Adrian Liston, Rachel E. Kohler, Scott Townley, Sarah Haylock-Jacobs, Iain Comerford, Adriana C. Caon, Julie Webster, Jodie M. Harrison, Jeremy Swann, Ian Clark-Lewis, Heinrich Korner, Shaun R. McColl, Inhibition of CCR6 Function Reduces the Severity of Experimental Autoimmune Encephalomyelitis via Effects on the Priming Phase of the Immune Response Journal of Immunology. ,vol. 182, pp. 3121- 3130 ,(2009) , 10.4049/JIMMUNOL.0713169
Melanie R. Shakespear, Maria A. Halili, Katharine M. Irvine, David P. Fairlie, Matthew J. Sweet, Histone deacetylases as regulators of inflammation and immunity. Trends in Immunology. ,vol. 32, pp. 335- 343 ,(2011) , 10.1016/J.IT.2011.04.001
Z. Zhang, Z.-Y. Zhang, Y. Wu, H.J. Schluesener, Valproic acid ameliorates inflammation in experimental autoimmune encephalomyelitis rats. Neuroscience. ,vol. 221, pp. 140- 150 ,(2012) , 10.1016/J.NEUROSCIENCE.2012.07.013
Zhenzhen Ge, Yurong Da, Zhenyi Xue, Kai Zhang, Hao Zhuang, Meiyu Peng, Yan Li, Wen Li, Alain Simard, Junwei Hao, Zhi Yao, Rongxin Zhang, Vorinostat, a histone deacetylase inhibitor, suppresses dendritic cell function and ameliorates experimental autoimmune encephalomyelitis Experimental Neurology. ,vol. 241, pp. 56- 66 ,(2013) , 10.1016/J.EXPNEUROL.2012.12.006
Kenneth K. Lee, Jerry L. Workman, Histone acetyltransferase complexes: one size doesn't fit all Nature Reviews Molecular Cell Biology. ,vol. 8, pp. 284- 295 ,(2007) , 10.1038/NRM2145