Closantel sodium injection and preparation method thereof

作者: Chen Xiaoli , Fan Zhijie , Wei Cunzhu , Yan Hufeng , Xu Chaojun

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摘要: Closantel sodium injection belongs to the field of medicines. The closantel is prepared by mixing sodium, hydroxypropyl cyclodextrin and povidone according a specific proportion. adding flexible side chain on basis cyclodextrin, cavity length achieve better matching rate, therefore, can be well enclosed, stability increased. Moreover, povidone, effects cosolvent compatilizer played, synergy effect ensures that relatively high, long time storage achieved. preparation method has advantages operation simple convenient, device requirements are not so quickly efficiently produced.

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