Proximal protein tyrosine kinases in immunoreceptor signaling.
作者： Sylvain Latour , André Veillette
DOI: 10.1016/S0952-7915(00)00219-3
关键词:
摘要: Abstract Immunoreceptor engagement results in the sequential activation of several classes protein tyrosine kinases, including Src and Syk/Zap-70 families. Recent progress has been made our understanding regulation function these molecules. First, it was revealed that membrane compartmentation kinases may be essential for their proper biological function. Second, family were found to act not only as positive regulators, but also inhibitors cell activation. Third, appreciated Csk, a potent inhibitor is regulated by an assortment protein–protein interactions. Fourth, differences Syk Zap-70 observed, suggesting significant distinctions purpose two immunoreceptor signaling. And fifth, suggested proximal implicated immunoreceptor-mediated signal transduction degradation via binding c-Cbl, ubiquitin ligase.
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sci-hub.se 参考文章(62)
Weiguo Zhang, Ronald P Trible, Lawrence E Samelson, LAT Palmitoylation: Its Essential Role in Membrane Microdomain Targeting and Tyrosine Phosphorylation during T Cell Activation Immunity. ,vol. 9, pp. 239- 246 ,(1998) , 10.1016/S1074-7613(00)80606-8
D. H. Chu, H. Spits, J. F. Peyron, R. B. Rowley, J. B. Bolen, A. Weiss, The Syk protein tyrosine kinase can function independently of CD45 or Lck in T cell antigen receptor signaling. The EMBO Journal. ,vol. 15, pp. 6251- 6261 ,(1996) , 10.1002/J.1460-2075.1996.TB01015.X
J. F. Cloutier, A. Veillette, Association of inhibitory tyrosine protein kinase p50csk with protein tyrosine phosphatase PEP in T cells and other hemopoietic cells. The EMBO Journal. ,vol. 15, pp. 4909- 4918 ,(1996) , 10.1002/J.1460-2075.1996.TB00871.X
Masahiro Kawabuchi, Yoshinori Satomi, Toshifumi Takao, Yasutsugu Shimonishi, Shigeyuki Nada, Katsuya Nagai, Alexander Tarakhovsky, Masato Okada, Transmembrane phosphoprotein Cbp regulates the activities of Src-family tyrosine kinases. Nature. ,vol. 404, pp. 999- 1003 ,(2000) , 10.1038/35010121
Colin R. F. Monks, Benjamin A. Freiberg, Hannah Kupfer, Noah Sciaky, Abraham Kupfer, Three-dimensional segregation of supramolecular activation clusters in T cells Nature. ,vol. 395, pp. 82- 86 ,(1998) , 10.1038/25764
B Crise, J.K. Rose, Identification of palmitoylation sites on CD4, the human immunodeficiency virus receptor. Journal of Biological Chemistry. ,vol. 267, pp. 13593- 13597 ,(1992) , 10.1016/S0021-9258(18)42253-3
Koubun Yasuda, Atsushi Kosugi, Fumie Hayashi, Shin-ichiroh Saitoh, Masakazu Nagafuku, Yoshiko Mori, Masato Ogata, Toshiyuki Hamaoka, Serine 6 of Lck Tyrosine Kinase: A Critical Site for Lck Myristoylation, Membrane Localization, and Function in T Lymphocytes Journal of Immunology. ,vol. 165, pp. 3226- 3231 ,(2000) , 10.4049/JIMMUNOL.165.6.3226
Marc Daëron, Victor L. J. Tybulewicz, John C. Cambier, Wolf H. Fridman, Dana C. Fong, Martin Turner, Odile Malbec, Fcε Receptor I-Associated lyn-Dependent Phosphorylation of Fcγ Receptor IIB During Negative Regulation of Mast Cell Activation Journal of Immunology. ,vol. 160, pp. 1647- 1658 ,(1998)
J C Cambier, L I Pao, Syk, but not Lyn, recruitment to B cell antigen receptor and activation following stimulation of CD45- B cells. Journal of Immunology. ,vol. 158, pp. 2663- 2669 ,(1997)
Wallace Y. Langdon, Christine B. F. Thien, David D. L. Bowtell, Perturbed regulation of ZAP-70 and sustained tyrosine phosphorylation of LAT and SLP-76 in c-Cbl-deficient thymocytes. Journal of Immunology. ,vol. 162, pp. 7133- 7139 ,(1999)