Mechanism of phospholipid biosynthesis in Escherichia coli: acyl-CoA synthetase is not required for the incorporation of intracellular free fatty acids into phospholipid.
作者： Tapas K. Ray , John E. Cronan
DOI: 10.1016/0006-291X(76)90550-7
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摘要: Abstract Previous results have shown that acyl-CoA synthetase is required both for the incorporation of exogenous fatty acids into phospholipids E. coli and transport cell. We demonstrated not intracellular free phospholipid. This finding indicates role this enzyme in exogenously supplied primarily at level acid transport.
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sci-hub.se 参考文章(18)
E M Barnes, S J Wakil, Studies on the Mechanism of Fatty Acid Synthesis XIX. PREPARATION AND GENERAL PROPERTIES OF PALMITYL THIOESTERASE Journal of Biological Chemistry. ,vol. 243, pp. 2955- 2962 ,(1968) , 10.1016/S0021-9258(18)93365-X
D R Lueking, H Goldfine, The involvement of guanosine 5-diphosphate-3-diphosphate in the regulation of phospholipid biosynthesis in Escherichia coli. Lack of ppGpp inhibition of acyltransfer from acyl-ACP to sn-glycerol 3-phosphate. Journal of Biological Chemistry. ,vol. 250, pp. 4911- 4917 ,(1975) , 10.1016/S0021-9258(19)41255-6
Tapas K. Ray, John E. Cronan, Richard D. Mavis, P. Roy Vagelos, The Specific Acylation of Glycerol 3-Phosphate to Monoacylglycerol 3-Phosphate in Escherichia coli EVIDENCE FOR A SINGLE ENZYME CONFERRING THIS SPECIFICITY Journal of Biological Chemistry. ,vol. 245, pp. 6442- 6448 ,(1970) , 10.1016/S0021-9258(18)62628-6
Giovanna F. Ames, Lipids of Salmonella typhimurium and Escherichia coli: Structure and Metabolism Journal of Bacteriology. ,vol. 95, pp. 833- 843 ,(1968) , 10.1128/JB.95.3.833-843.1968
William M. Bonner, Konrad Bloch, Purification and Properties of Fatty Acyl Thioesterase I from Escherichia coli Journal of Biological Chemistry. ,vol. 247, pp. 3123- 3133 ,(1972) , 10.1016/S0021-9258(19)45222-8
J E Cronan, L J Weisberg, R G Allen, Regulation of membrane lipid synthesis in Escherichia coli. Accumulation of free fatty acids of abnormal length during inhibition of phospholipid synthesis. Journal of Biological Chemistry. ,vol. 250, pp. 5835- 5840 ,(1975) , 10.1016/S0021-9258(19)41128-9
TK Ray, JE Cronan, Acylation of sn-glycerol 3-phosphate in Escherichia coli. Study of reaction with native palmitoyl-acyl carrier protein. Journal of Biological Chemistry. ,vol. 250, pp. 8422- 8427 ,(1975) , 10.1016/S0021-9258(19)40775-8
Robert M. Bell, Mutants of Escherichia coli Defective in Membrane Phospholipid Synthesis: Macromolecular Synthesis in an sn-Glycerol 3-Phosphate Acyltransferase Km Mutant Journal of Bacteriology. ,vol. 117, pp. 1065- 1076 ,(1974) , 10.1128/JB.117.3.1065-1076.1974
M A Polokoff, R M Bell, Millipore filter assay for long-chain fatty acid:CoASH ligase activity using 3H-labeled coenzyme A. Journal of Lipid Research. ,vol. 16, pp. 397- 402 ,(1975) , 10.1016/S0022-2275(20)34533-8
Tapas K. Ray, Vladimir P. Skipski, Marion Barclay, Edward Essner, Francis M. Archibald, Lipid Composition of Rat Liver Plasma Membranes Journal of Biological Chemistry. ,vol. 244, pp. 5528- 5536 ,(1969) , 10.1016/S0021-9258(18)63595-1