Compositions containing, methods involving, and uses of non-natural amino acids and polypeptides

作者: Russell Driver , Junjie Liu , Thea Norman , Zhenwei Miao

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摘要: Disclosed herein are non-natural amino acids and polypeptides that include at least one acid, methods for making such polypeptides. The acids, by themselves or as a part of polypeptide, can wide range possible functionalities, but typical have oxime, carbonyl, dicarbonyl, and/or hydroxylamine group. Also disclosed acid further modified post-translationally, effecting modifications, purifying Typically, the Further using polypeptides, including therapeutic, diagnostic, other biotechnology uses.

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