Clinical Outcomes of Dacryocystorhinostomy With or Without Intraoperative Use of Mitomycin C: A Systematic Review and Meta-Analysis
作者： Zhuyun Qian , Yidan Zhang , Xianqun Fan
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摘要: Abstract Purpose: To examine the possible benefit of intraoperative use mitomycin C (MMC) application in dacryocystorhinostomy (DCR) and to assess its potential risk. Methods: Systematic review meta-analysis randomized-controlled trials (RCTs). A comprehensive literature search was performed according a protocol set advance. The participants included 811 patients which 820 eyes were sampled for 14 RCTs. Only pertinent RCTs identified this meta-analysis. primary efficacy measure “patency irrigation” at follow-up end point. subjective outcome “symptom relief” also extracted as secondary measure. For each study, relative risk extracted. Heterogeneity, publication bias, subgroup, meta-regression analyses performed. Results: RevMan version 5.0 software used statistical analysis. In measure, MMC can significantly increase rate [risk ratio (RR), 1.10; 95% co...
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