Synthesis of amide derivatives of some nonsteroidal antiinflammatory drugs as potential pro-drugs
作者： Ilkay Kücükgüzel , Necla Kulabas , Irem Set
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摘要: The present invention presents a method for masking acidic groups existing in NSAI drugs to prevent or reduce the hazards of GI (gastrointestinal) system. developed comprises production new amide derivatives by methyl esterification carboxylic acid which belong and then amidification same. is also related are suitable use as pro-drugs.
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