Maternal cocaine abuse: the spectrum of radiologic abnormalities in the neonatal CNS.

摘要: The purpose of this study was to determine the pattern and frequency CNS abnormalities in offspring cocaine-abusing mothers. group consisted a retrospective review all neonates born or admitted our neonatal intensive care unit over 1-year period who met criteria for maternal cocaine abuse (43 patients). A control (62 patients) obtained from patients seen during same interval cases were matched gestational age race. radiologic studies analyzed by two independent reviewers, assessed means sonography, CT, MR. By matching groups age, we eliminated higher prematurity. This allowed us if use associated with any intracranial other than those hemorrhage, ventricular enlargement, periventricular leukomalacia not significantly different between groups. cortical infarction 17% 2% group. major congenital malformation 12% 0% All five malformations midline abnormalities, particularly neural tube defects. It is postulated that statistically significant stroke babies abusers related vasospasm caused when used third first trimesters, respectively.