作者: Christine Coulondre , Jeffrey H. Miller , Philip J. Farabaugh , Walter Gilbert
DOI: 10.1038/274775A0
关键词:
摘要: In the lacI gene of Escherichia coli spontaneous base substitution hotspots occur at 5-methylcytosine residues. The hotspots disappear when the respective cytosines are not methylated…