作者: Marc Mertens , Katja Schmidt , Aykut Ozkul , Martin H. Groschup
DOI: 10.1016/J.ANTIVIRAL.2013.02.007
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摘要: Climatic, environmental and economic changes, as well the steadily increasing global trade personal mobility provide ample opportunities for emerging pathogens with zoonotic potential to spread previously unaffected countries. Crimean-Congo hemorrhagic fever virus (CCHFV) is considered be one of major disease threats spreading within European Union following an expanding distribution its main vector, ticks genus Hyalomma. Every year more than 1000 human CCHF cases are reported from countries southeastern Europe Turkey. CCHFV can cause high case fatality rates transmitted human. There no vaccine prophylaxis therapeutic interventions available at present. Several EU-funded research projects focus currently on which highlights awareness this problem level. As public health deals questions prevention a population level rather healing individual level, analysis existing data plays fundamental role minimize epidemic potential, by reducing infection risks, manage outbreaks. This review gives summary current knowledge interface between CCHFV. Based knowledge, guidelines risk classification region outbreak given. will assist decision makers authorities in understanding scenarios deciding effective countermeasures, veterinary scientists highlighting gaps knowledge.