Bioadhesive Drug Delivery Systems : Fundamentals, Novel Approaches, and Development

摘要: Fundamentals of Bioadhesion Definitions, Mechanisms, and Theories Donald E. Chickering III Edith Mathiowitz The Role Water Movement Polymer Hydration in Mucoadhesion John D. Smart A Rheological Approach to Explain the Mucoadhesive Behavior Hydrogels Carla Marcella Caramella, Silvia Rossi, Maria Cristina Bonferoni Functional Histology Epithelia Relevant for Drug Delivery: Respiratory Tract, Digestive Eye, Skin, Vagina Udo Schumacher Dietlind Biochemical Aspects Mucus Mucin-Type Glycoproteins Barry James Campbell Methods Evaluating Bioadhesive Interactions Adaptation a Microbalance Measure Properties Microspheres III, Camilla A. Santos, Novel Magnetic Technique Benjamin Hertzog Principles Skin Adhesion Measuring Transdermal Systems Michael Horstmann, Walter Muller, Bodo Asmussen Force Microscopy Cells zur Muhlen, P. Koschinski, S. Gehring, Robert Ros, Louis Tiefenhauer, Eleonore Haltner, Claus-Michael Lehr, Uwe Hartmann, Falk Schwesinger, Pluckthun Direct Measurement Molecular-Level Forces Biological Schneider Matthew Tirrell Centrifugation Method Two-Dimensional Binding Characteristics Receptor-Ligand Interaction Cheng Zhu, W. Piper, Swerlick Concepts Strategies Delivery Multifunctional Polymers Peroral Peptide Drugs Henrik L. Luessen, J. Coos Verhoef, (Bert) G. de Boer, H. Junginger, Bas Leeuw, Gerrit Borchard, Lehr Chitosan Derivatives as Absorption Enhancers Across Mucosal F. Kotze, M. Thanou, Plant Lectins Oral Different Parts Gastrointestinal Tract Arpad Pusztai, Susan Bardocz, Stanley B. Ewen Bacterial Invasion Factors Second-Generation Bioadhesives Easson, Dieter Jahn PEG-Containing Acrylate Copolymers with Improved Amir Shojaei Xiaoling Li Bioadhesive, Bioerodible Increased Intestinal Uptake Gerardo Carino, Jules Jacob, C. Chen, Hertzog, Development Issues Systems: Products Clinical Trials Formulation Approaches Yohko Akiyama Naoki Nagahara Formulations Nasal Lisbeth Illum Buccal Patches Jian-Hwa Guo Karsten Cremer Vaginal Calcitonin by Hyaluronic Acid Julie Richardson Trevor I. Armstrong Ocular Marco Fabrizio Saettone, Susi Burgalassi, Patrizia Chetoni Preparations Topical Dosage Forms Yoshiharu Machida Tsuneji Nagai