Narrowed lumen of the right coronary artery in chronic Chagasic patients is associated with ischemic lesions of segmental thinnings of ventricles.

摘要: Thinning of myocardial segments, mainly at the apex and basal posterior region left ventricle, are frequent lesions in chronic chagasic cardiopathy (CCC), but still without a well determined etiology. Previously we found severe microvascular dilatation that could cause ischemia watershed regions. In this study analyzed whether narrowness epicardial coronary arteries CCC might explain these thinned ventricular lesions. Two groups dilated hearts with similar weights were compared: eleven from patients versus four cardiomyopathy (IDCM). As normal controls studied three non nor- mal weight hearts. There no atherosclerotic plaques main branches cross-sectional luminal areas proximal distal segments histologically measured. It was presented lower mean area right artery (RCA) branch than IDCM, (4.3 ± 1.4 vs 6.6 2.0 mm 2 ; p= 0.02) (1.6 1.0 3.4 0.9 0.01) statis- tical differences (2.7 1.3 1.5 0.3 ) proxi- (p= 0.2) (p=0.11) sections. conclusion thinning ventricu- lar wall seems to be ischemic peripheral terri- tory irrigated by artery, possibly due steal phenome- coronary, induced micro vessels dilatation.