Chromatin Damage and Male Infertility
作者： Denny Sakkas , Davide Bizzaro , Gian C. Manicardi
DOI: 10.1007/978-1-59745-176-5_20
关键词:
摘要: There is accumulating evidence linking sperm chromatin damage to poor reproductive outcome. The associated anomalies that manifest themselves as breaks in the nuclear DNA, aberrant ratios of protamine and histones chromatin, presence apoptotic marker proteins ejaculated spermatozoa. This chapter examines mechanisms involved generating during spermatogenesis human, techniques used test how they may affect outcome, reduce risk using spermatozoa with damage.
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