Tri-aza macrocycles and metal complexes thereof

摘要: Tri-aza macrocycles of formula (1), wherein m and n, which may be the same or different, is each zero an integer 1, 2, 3; p 1 2; q from to 6 inclusive; R1, R2 R3, a hydrogen atom alkyl, alkoxyalkyl, -CO2H, -SO3H, PO3H2 aryl group; L covalent bond linker Z reactive functional group, with proviso that when metal complexes and/or salts thereof are described together processes for their preparation compositions containing them. The compounds useful imaging in treatment abnormal cell disorders, such as tumours, particularly suitable coupling other molecules proteins use diagnosis therapy.