Daisy Chain Rotaxanes Made from Interlocked DNA Nanostructures.
作者： Johannes Weigandt , Chia-Ling Chung , Stefan-S. Jester , Michael Famulok
关键词:
摘要: We report the stepwise assembly of supramolecular daisy chain rotaxanes (DCR) made double-stranded DNA: Small dsDNA macrocycles bearing an axle assemble into a pseudo-DCR precursor that was connected to rigid DNA stoppers form DCR with hybridized axles. In presence release oligodeoxynucleotides (rODNs), are released from their respective hybridization sites on axles, leading stable mechanically interlocked DCRs. Besides expected threaded DCRs, certain amounts externally structures were observed, which dissociate dumbbell in rODNs. show genuine DCRs have significantly higher degrees freedom movement along thread than precursors. Interlocking might serve as versatile principle for constructing functional nanostructures where subunits is restricted within precisely confined tolerance ranges.
core.ac.uk
mpg.de
sci-hub.se 参考文章(44)
Oleg Lukin, Fritz Vögtle, Verknoten und Durchfädeln von Molekülen: Chemie und Chiralität molekularer Knoten und ihrer Ensembles Angewandte Chemie. ,vol. 117, pp. 1480- 1501 ,(2005) , 10.1002/ANGE.200460312
Jonas J. Funke, Hendrik Dietz, Placing molecules with Bohr radius resolution using DNA origami Nature Nanotechnology. ,vol. 11, pp. 47- 52 ,(2016) , 10.1038/NNANO.2015.240
Moritz K. Beissenhirtz, Itamar Willner, DNA-based machines Organic and Biomolecular Chemistry. ,vol. 4, pp. 3392- 3401 ,(2006) , 10.1039/B607033G
Jürgen Rotzler, Marcel Mayor, Molecular daisy chains Chemical Society Reviews. ,vol. 42, pp. 44- 62 ,(2013) , 10.1039/C2CS35217F
M. G. L. van den Heuvel, C. Dekker, Motor proteins at work for nanotechnology. Science. ,vol. 317, pp. 333- 336 ,(2007) , 10.1126/SCIENCE.1139570
Sai Bi, Yangyang Cui, Li Li, Ultrasensitive detection of mRNA extracted from cancerous cells achieved by DNA rotaxane-based cross-rolling circle amplification The Analyst. ,vol. 138, pp. 197- 203 ,(2013) , 10.1039/C2AN36118C
Chengde Mao, Weiqiong Sun, Nadrian C. Seeman, Assembly of Borromean rings from DNA Nature. ,vol. 386, pp. 137- 138 ,(1997) , 10.1038/386137B0
Kyle Lund, Anthony J. Manzo, Nadine Dabby, Nicole Michelotti, Alexander Johnson-Buck, Jeanette Nangreave, Steven Taylor, Renjun Pei, Milan N. Stojanovic, Nils G. Walter, Erik Winfree, Hao Yan, Molecular robots guided by prescriptive landscapes Nature. ,vol. 465, pp. 206- 210 ,(2010) , 10.1038/NATURE09012
Tao Li, Finn Lohmann, Michael Famulok, Interlocked DNA nanostructures controlled by a reversible logic circuit. Nature Communications. ,vol. 5, pp. 4940- 4940 ,(2014) , 10.1038/NCOMMS5940
J. Fraser Stoddart, The chemistry of the mechanical bond Chemical Society Reviews. ,vol. 38, pp. 1802- 1820 ,(2009) , 10.1039/B819333A