The mastoparanogen from wasp
作者： Xueqing Xu , Hailong Yang , Haining Yu , Jianxu Li , Ren Lai
DOI: 10.1016/J.PEPTIDES.2006.09.003
关键词:
摘要: Abstract Mastoparans are a family of small peptides identified from the venom hymenopteroid insects. Although they have been characterized as early 1979, and so far recognized leading biomolecule in potential drug therapy, their precursors, mastoparanogen, still not determined. In this paper, several mastoparans wasp Vespa magnifica (Smith) reported. The cDNA mastoparanogen is 236 base pairs length, encodes 40 amino acid residues, including N-terminal acidic fragment C-terminal mature basic mastoparan, which contain multiple residues tetradecapeptide with three lysines, INLKAIAALAKKLL G , respectively. glycine at end donator –NH 4 for amidation leucine C-terminal. As we know, first report precursor animal mastoparan.
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