Rapid screening method for effectors of signal transduction
作者： Eugene W. Napolitano , Daria Mochly-Rosen , Lawrence M. Kauvar , Dorit Ron
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摘要: Methods for assessing libraries of candidate modulators intracellular signaling transmission pathways are described. The methods assess the ability candidates from library to inhibit binding peptides which represent participants in as either a signal-generating protein or its cognate partner at noncatalytic site. Specific useful this regard have been identified.
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