Viral causes of feline lymphoma: Retroviruses and beyond
作者： Julia Beatty
DOI: 10.1016/J.TVJL.2014.05.026
关键词:
摘要: The most widely recognised cause of feline lymphoma is the gammaretrovirus leukaemia virus (FeLV). Research into mechanisms cellular transformation employed by FeLV and other oncogenic retroviruses has provided as much information on regulation eukaryotic cell growth differentiation it about cancer. recognition that a cancer viral opens up possibility novel treatments spare host from cytotoxic side-effects specifically targeting virus, or host's immune response to it. ultimate prize for viral-associated cancers their prevention. Vaccination changes in management practices have seen global prevalence infection fall and, with it, incidence FeLV-related cancers. Remarkably, face this success, remains high. At least one lentivirus immunodeficiency (FIV), accounts some these cases. Transformation FIV involves incompletely understood are distinct those FeLV. This review will focus current understanding FeLV-associated FIV-associated consider whether yet more aetiologies could be waiting discovered.
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