Cardiorespiratory responses to incremental exercise in patients with asbestos-related pleural thickening and normal or slightly abnormal lung function.

摘要: An increasing number of patients with asbestos exposure are being identified pleural thickening (PT) alone, little or no impairment in standard tests lung function despite their frequent complaint dyspnea. We have employed incremental cardiorespiratory exercise testing to evaluate the types and mechanisms 23 such patients. All had normal fields on radiographic examinations (group 1, n = 12) minimally reduced 2A slight restriction, 5, group 2B, obstruction, 6), function. Excessive ventilation was common all groups, but especially 2B. Abnormal dead space (VD/VT) more groups (4/5) 2B (4/6) than 1 (3/12). It associated O2 desaturation three B. Cardiovascular abnormalities were rare (1/23). provide a basis for symptom dyspnea these