Disposition of Proteins and Lipids in Synaptic Membrane Compartments Is Altered in Q175/Q7 Huntington's Disease Mouse Striatum.

作者: Ellen Sapp , Marian DiFiglia , Xueyi Li , Maria Iuliano , Kimberly B Kegel-Gleason

DOI: 10.3389/FNSYN.2021.618391

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摘要: Dysfunction at synapses is thought to be an early change contributing to cognitive, psychiatric and motor disturbances in Huntington’s disease (HD). In neurons, mutant Huntingtin …

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