作者: R.A. OOSTERBAAN , H.S. JANSZ
DOI: 10.1016/B978-1-4831-9710-4.50008-8
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摘要: Publisher Summary The enzymes, cholinesterases, esterases, and lipases, catalyze the hydrolysis of carboxyl esters. It has been shown that enzymatic ester cleavage is governed by a mechanism, which similar for different enzymes. Evidence derived from studies on kinetics interaction these enzymes with substrates inhibitors specifically chemical analysis active site. similarity in mechanism might be because presence common or related site esterases. This chapter presents information their inhibitors, contributes to an understanding molecular basis general hydrolysis. further data relevant substrate specificities individual Enzymes hydrolyze choline esters are usually sub-divided into acetyl-, propionyl-, butyryl- benzoyl-cholinesterases depending hydrolyzed at highest rate. ability act undissolved proposed differentiate lipases other carboxylesterases like ali-esterases only solution.