Aktuelle Therapieoptionen bei rezidivierenden Kopf-Hals-Tumoren
作者： A. Boehm , G. Wichmann , C. Mozet , A. Dietz
DOI: 10.1007/S00106-010-2156-0
关键词:
摘要: Recurrent disease is one of the main reasons for persistently poor prognosis squamous cell carcinoma head and neck (HNSCC; European 5-year survival, 42%). The treatment option primary secondary malignancy as well recurrent surgical therapy. If R0 resection (resection margin >5 mm) a tumor not viable, survival probability reduced by 50%. In or tumors with R1- -2 in presence non-resectable metastases, palliative situation results more than 80% cases. case surgery following radiotherapy radiochemotherapy, attention should be paid to criteria salvage (tissue perfusion, fibrosis, wound healing) procedure adapted focus on functionality. relapse, can potentially supplemented adjuvant therapy protocols such (re-) irradiation, possibly chemotherapeutic agents targeted therapies. Interdisciplinary collaboration discussions take place context board.
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