MRI-guided stereotaxic brain surgery in the infant and adult common marmoset.
作者： Inaki-Carril Mundinano , Paul A Flecknell , James A Bourne , None
关键词:
摘要: In the past decade, New World common marmoset (Callithrix jacchus) has taken a seminal position in neurobiological research, fueled part by its smooth cortical sheet, which allows areas to be easily accessed current technologies on dorsal surface of brain. this protocol, we describe method for precision placement agents (e.g., tracers or neurotoxins) into small brain regions infant and adult marmoset, using an MRI-guided approach. This strategy uses protocol prolonged anesthesia without need intubation that have recently developed, alongside appropriate analgesia monitoring. The can readily adapted used together with advanced research techniques, such as two-photon microscopy optical imaging. Including 5-d postoperative care plan, takes 7 d complete. requires team personnel experienced handling, small-animal neurosurgery; assistant monitoring animal assisting anesthesia; MRI technician.
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sci-hub.se 参考文章(19)
Michal T. Krauze, Ryuta Saito, Charles Noble, Matyas Tamas, John Bringas, John W. Park, Mitchel S. Berger, Krystof Bankiewicz, Reflux-free cannula for convection-enhanced high-speed delivery of therapeutic agents Journal of Neurosurgery. ,vol. 103, pp. 923- 929 ,(2005) , 10.3171/JNS.2005.103.5.0923
Leon Teo, James A. Bourne, A reproducible and translatable model of focal ischemia in the visual cortex of infant and adult marmoset monkeys. Brain Pathology. ,vol. 24, pp. 459- 474 ,(2014) , 10.1111/BPA.12129
T. Gill, N.U. Barua, M. Woolley, A.S. Bienemann, D.E. Johnson, S.O'Sullivan, G. Murray, C. Fennelly, O. Lewis, C. Irving, M.J. Wyatt, P. Moore, S.S. Gill, In vitro and in vivo testing of a novel recessed-step catheter for reflux-free convection-enhanced drug delivery to the brain Journal of Neuroscience Methods. ,vol. 219, pp. 1- 9 ,(2013) , 10.1016/J.JNEUMETH.2013.06.008
C. E. Warner, W. C. Kwan, J. A. Bourne, The early maturation of visual cortical area MT is dependent on input from the retinorecipient medial portion of the inferior pulvinar. The Journal of Neuroscience. ,vol. 32, pp. 17073- 17085 ,(2012) , 10.1523/JNEUROSCI.3269-12.2012
, The common marmoset genome provides insight into primate biology and evolution Nature Genetics. ,vol. 46, pp. 850- 857 ,(2014) , 10.1038/NG.3042
Jude F. Mitchell, David A. Leopold, The marmoset monkey as a model for visual neuroscience. Neuroscience Research. ,vol. 93, pp. 20- 46 ,(2015) , 10.1016/J.NEURES.2015.01.008
Erika Sasaki, Prospects for genetically modified non-human primate models, including the common marmoset Neuroscience Research. ,vol. 93, pp. 110- 115 ,(2015) , 10.1016/J.NEURES.2015.01.011
Hironobu Tokuno, Ikuko Tanaka, Yoshitomo Umitsu, Toshikazu Akazawa, Yasuhisa Nakamura, Web-accessible digital brain atlas of the common marmoset (Callithrix jacchus). Neuroscience Research. ,vol. 64, pp. 128- 131 ,(2009) , 10.1016/J.NEURES.2009.02.003
John D. Newman, William M. Kenkel, Emily C. Aronoff, Nicholas A. Bock, Molly R. Zametkin, Afonso C. Silva, A combined histological and MRI brain atlas of the common marmoset monkey, Callithrix jacchus. Brain Research Reviews. ,vol. 62, pp. 1- 18 ,(2009) , 10.1016/J.BRAINRESREV.2009.09.001
Jaco Bakker, Joost J Uilenreef, Eva RJ Pelt, Herbert PM Brok, Edmond J Remarque, Jan AM Langermans, Comparison of three different sedative-anaesthetic protocols (ketamine, ketamine-medetomidine and alphaxalone) in common marmosets (Callithrix jacchus) BMC Veterinary Research. ,vol. 9, pp. 113- 113 ,(2013) , 10.1186/1746-6148-9-113