Radiotracers in Oncology

摘要: Radiopharmaceuticals are able to give functional information about systems, organs or cells. This can be different cell mechanisms molecular pathways. In terms of systems this assessed through biodistribution studies while that in cells evaluated more detailed research, like calculation influx and efflux indexes binding studies. Moreover recent advances understanding the underlying disease, allow diagnosis early stages sometimes several months before onset morphological changes translate disease. These approaches especially important oncology. The nuclear medicine allows map quantify local related metabolic pathways involved malignant transformation tumoral proliferation. We made a longitudinal approach development we show how it is possible evaluate some steps using get not only situation tissue but also its therapeutic response. Therefore, covering issues tumor proliferation, metabolism, angiogenesis, hypoxia, apoptosis, receptors multidrug resistance confirm role on detection, treatment cancer follow-up.