Immunophenotype of Gastric Tumors Unveils a Pleiotropic Role of Regulatory T Cells in Tumor Development
作者： Marieke E Ijsselsteijn , Sara P Teles , Joaquín J Maqueda , Afonso P Basto , João T Barata
关键词:
摘要: … Hence, we established direct co-cultures of T cells and 3D GC spheroids recapitulating the … Our 3D co-culture system not only closely mimics tumors from GC patients, but also their …
mdpi.com
sci-hub.st 参考文章(36)
Tetsuro Sasada, Motohide Kimura, Yuka Yoshida, Michiyuki Kanai, Arimichi Takabayashi, None, CD4+CD25+ regulatory T cells in patients with gastrointestinal malignancies: possible involvement of regulatory T cells in disease progression. Cancer. ,vol. 98, pp. 1089- 1099 ,(2003) , 10.1002/CNCR.11618
Wei Tan, Weizhou Zhang, Amy Strasner, Sergei Grivennikov, Jin Q. Cheng, Robert M. Hoffman, Michael Karin, Tumour-infiltrating regulatory T cells stimulate mammary cancer metastasis through RANKL–RANK signalling Nature. ,vol. 470, pp. 548- 553 ,(2011) , 10.1038/NATURE09707
Thomas R. Malek, Iris Castro, Interleukin-2 Receptor Signaling: At the Interface between Tolerance and Immunity Immunity. ,vol. 33, pp. 153- 165 ,(2010) , 10.1016/J.IMMUNI.2010.08.004
Yoshiki Mizukami, Koji Kono, Yoshihiko Kawaguchi, Hidenori Akaike, Kazuyasu Kamimura, Hidemitsu Sugai, Hideki Fujii, CCL17 and CCL22 chemokines within tumor microenvironment are related to accumulation of Foxp3+ regulatory T cells in gastric cancer. International Journal of Cancer. ,vol. 122, pp. 2286- 2293 ,(2008) , 10.1002/IJC.23392
Koji Kono, Hiromichi Kawaida, Akihiro Takahashi, Hidemitsu Sugai, Kosaku Mimura, Naoto Miyagawa, Hideo Omata, Hideki Fujii, CD4(+)CD25high regulatory T cells increase with tumor stage in patients with gastric and esophageal cancers. Cancer Immunology, Immunotherapy. ,vol. 55, pp. 1064- 1071 ,(2006) , 10.1007/S00262-005-0092-8
Matthias Haas, Arno Dimmler, Werner Hohenberger, Gerhard G Grabenbauer, Gerald Niedobitek, Luitpold V Distel, Stromal regulatory T-cells are associated with a favourable prognosis in gastric cancer of the cardia BMC Gastroenterology. ,vol. 9, pp. 65- 65 ,(2009) , 10.1186/1471-230X-9-65
Seigo Kashimura, Zenichiro Saze, Masanori Terashima, Nobutoshi Soeta, Satoshi Ohtani, Fumihiko Osuka, Michihiko Kogure, Mitsukazu Gotoh, CD83+ dendritic cells and Foxp3+ regulatory T cells in primary lesions and regional lymph nodes are inversely correlated with prognosis of gastric cancer Gastric Cancer. ,vol. 15, pp. 144- 153 ,(2012) , 10.1007/S10120-011-0090-9
Annamaria Ruzzo, Mauro Magnani, Giuseppe Tonini, Carla Rabitti, Francesco Graziano, Giuseppe Perrone, Pier Adelchi Ruffini, Vincenzo Catalano, Cathie Spino, Daniele Santini, Pietro Muretto, Chiara Spoto, Costantino Zingaretti, Valerio Sisti, Paolo Alessandroni, Paolo Giordani, Andrea Cicetti, Silvia D’Emidio, Sergio Morini, Intratumoural FOXP3-positive regulatory T cells are associated with adverse prognosis in radically resected gastric cancer. European Journal of Cancer. ,vol. 44, pp. 1875- 1882 ,(2008) , 10.1016/J.EJCA.2008.05.017
Shuang Zhou, Zhenbing Shen, Yanna Wang, Huiying Ma, Shuchang Xu, Jie Qin, Long Chen, Huihong Tao, Zhiwei Zhen, Guolin Chen, Zhiqiang Zhang, Rilun Li, Honglei Xiao, Cuiping Zhong, Yaoqin Yang, Chunmin Liang, CCR7 Expression and Intratumoral FOXP3+ Regulatory T Cells are Correlated with Overall Survival and Lymph Node Metastasis in Gastric Cancer PLoS ONE. ,vol. 8, pp. e74430- ,(2013) , 10.1371/JOURNAL.PONE.0074430
Tae Jung Jang, The number of Foxp3-positive regulatory T cells is increased in Helicobacter pylori gastritis and gastric cancer Pathology Research and Practice. ,vol. 206, pp. 34- 38 ,(2010) , 10.1016/J.PRP.2009.07.019