作者: Derek Weycker , David Strutton , John Edelsberg , Reiko Sato , Lisa A. Jackson
DOI: 10.1016/J.VACCINE.2010.05.030
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摘要: We developed a model characterizing rates and costs of pneumococcal disease in the US to estimate expected annual clinical economic burden this condition among older adults. Among 91.5 million adults aged >or=50 years, 29,500 cases invasive disease, 502,600 nonbacteremic pneumonia, 25,400 pneumococcal-related deaths are estimated occur yearly; direct indirect total $3.7 billion $1.8 billion, respectively. Pneumococcal remains substantial adults, despite increased coverage with PPV23 benefits afforded by PCV7 vaccination young children.