Effect of Intravenous Paracetamol with Bupivacaine Scalp Nerve Block on Haemodynamics Response as Well as Anaesthetic Requirements during Supratentorial Craniotomies.

摘要: Noxious stimuli during craniotomy may encourage hypertension and tachycardia, which rise to morbidity in patients with intracranial hypertension. After a moderate level of postoperative pain observed. The objective this study was observe the effect intravenous paracetamol bupivacaine scalp nerve block (SNB) on haemodynamics response as well anaesthetic & analgesic requirements supratentorial craniotomies. This is single-blind, placebo-controlled, randomized clinical trial carried out Neurosurgery operation theatre from August 2015 July 2017 under supervision Department Anaesthesia, Analgesia Intensive Care Medicine Bangabandhu Sheikh Mujib Medical University, Dhaka, Bangladesh. A total 40 aged 18-60 years space occupying lesion undergoing general anaesthesia who were attended department Neurosurgery, BSMMU enrolled they divided randomly into two groups, 20 each. Group received 100ml normal saline infusion 0.25% (20ml) block, while B injection (1gm) (total 20ml) block. Statistical analyses obtained Packages for Social Sciences (SPSS-22). mean systolic blood pressure varied within range both groups. DBP remained significantly lower than that different follow up except at 30 minutes 60 after dura incision. However, MAP time interval. heart rate A. intraoperative propofol fentanyl decreased comparison combination provides better intra-operative haemodynamic stability neurosurgical compliances craniotomies anaesthesia.