Pyrrolidino-tetrahydroisoquinolines bearing pendant heterocycles as potent dual H3 antagonist and serotonin transporter inhibitors.
作者： John M. Keith , Leslie A. Gomez , Ann J. Barbier , Sandy J. Wilson , Jamin D. Boggs
DOI: 10.1016/J.BMCL.2007.03.043
关键词:
摘要: Abstract A series of novel and potent 6-heteroaryl-pyrrolidino-tetrahydroisoquinolines with dual histamine H3 antagonist/serotonin transporter inhibitor activity is described. In vitro in vivo data are discussed.
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