HEMATOLOGICAL EFFECTS AND METAL RESIDUE CONCENTRATIONS FOLLOWING CHRONIC DOSING WITH TUNGSTEN-IRON AND TUNGSTEN-POLYMER SHOT IN ADULT GAME-FARM MALLARDS

摘要: The U.S. Fish and Wildlife Service required a chronic dosing study that assessed the health reproductive effects of tungsten-iron tungsten-polymer shot in adult game-farm mallards (Anas platyrhynchos) prior to granting permanent approval for waterfowl hunting. Herein, we present on various hematologic parameters metal residue concentrations femur, liver, kidneys, gonads. Thirty-two-bird groups (sexes equal) were dosed orally with eight #4 steel (control), shot, or days 0, 30, 60, 90, 120 150 day trial (26 January 1998 25 June 1998). An additional 12 received lead (positive control) 0 study. Lead-dosed had significantly decreased hematocrit, hemoglobin concentration, whole-blood delta aminolevulinic acid dehydratase activity 7, as well significant changes...