Delayed Cerebral Ischemia After Subarachnoid Hemorrhage

作者: Nicolien K. de Rooij , Gabriel J.E. Rinkel , Jan Willem Dankbaar , Catharina J.M. Frijns

DOI: 10.1161/STROKEAHA.112.674291

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摘要: Background and Purpose—Established predictors of delayed cerebral ischemia after aneurysmal subarachnoid hemorrhage are large amounts extravasated blood poor clinical condition on admission. The predictive value other factors is uncertain. Methods—We searched MEDLINE (1960–2012) for clinical, laboratory, radiological routinely available within 72 hours hemorrhage. studies were categorized according to methodological quality. Crude data effect estimates (odds ratio [OR], hazard ratios, risk ratio) with 95% CI extracted, (re-)calculated pooled if possible. For every potential predictor we assessed all consistency (point in equal direction) relevance (size CI). Results—Fifty-two 33 included. There was strong evidence (≥3 high-quality studies) a higher smokers (pooled OR, 1.2; CI, 1.1–1.4), moderate (2...

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