Genetic studies of human apolipoproteins. XV. An overview of IEF immunoblotting methods to screen apolipoprotein polymorphisms.
作者： M.I. Kamboh , R.E. Ferrell
DOI: 10.1159/000153931
关键词:
摘要: Genetically determined structural variation in the gene products of various apolipoproteins plays a significant role modulating lipid levels population at large. However, due to tedious and cumbersome experimental problems involved, detailed characterization this genetic has been limited. The recent development simple sensitive isoelectric focusing immunoblotting methods circumvented these technically associated large extent, allowed us expand data on previously uncharacterized populations. We have reviewed here methods. A comprehensive listing allele frequencies also given for polymorphic apolipoproteins.
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B Sepehrnia, M I Kamboh, R E Ferrell, Genetic studies of human apolipoproteins. IV. Structural heterogeneity of apolipoprotein H (beta 2-glycoprotein I). American Journal of Human Genetics. ,vol. 42, pp. 452- 457 ,(1988)
C F Sing, J Davignon, Role of the apolipoprotein E polymorphism in determining normal plasma lipid and lipoprotein variation. American Journal of Human Genetics. ,vol. 37, pp. 268- 285 ,(1985)
M I Kamboh, R E Ferrell, Genetic studies of human apolipoproteins. I. Polymorphism of apolipoprotein A-IV. American Journal of Human Genetics. ,vol. 41, pp. 119- 127 ,(1987)
Erika Polz, Gerhard M. Kostner, The binding of β2
-glycoprotein-I to human serum lipoproteins FEBS Letters. ,vol. 102, pp. 183- 186 ,(1979) , 10.1016/0014-5793(79)80955-2
N S Lee, H B Brewer, J C Osborne, beta 2-Glycoprotein I. Molecular properties of an unusual apolipoprotein, apolipoprotein H. Journal of Biological Chemistry. ,vol. 258, pp. 4765- 4770 ,(1983) , 10.1016/S0021-9258(18)32490-6
J. E. Eichner, L. H. Kuller, M. I. Kamboh, R. E. Ferrell, G. P. Vogler, D. C. Rao, Phenotypic effects of apolipoprotein structural variation on lipid profiles. I. APO H and quantitative lipid measures in the healthy women study. Genetic Epidemiology. ,vol. 6, pp. 311- 318 ,(1989) , 10.1002/GEPI.1370060202
G R Warnick, J J Albers, A comprehensive evaluation of the heparin-manganese precipitation procedure for estimating high density lipoprotein cholesterol. Journal of Lipid Research. ,vol. 19, pp. 65- 76 ,(1978) , 10.1016/S0022-2275(20)41577-9
Charles C Allain, Lucy S Poon, Cicely S G Chan, W Richmond, Paul C Fu, Enzymatic determination of total serum cholesterol. Clinical Chemistry. ,vol. 20, pp. 470- 475 ,(1974) , 10.1093/CLINCHEM/20.4.470
H J Menzel, J P Kane, M J Malloy, R J Havel, A variant primary structure of apolipoprotein C-II in individuals of African descent. Journal of Clinical Investigation. ,vol. 77, pp. 595- 601 ,(1986) , 10.1172/JCI112342
Mohammad I. Kamboh, Robert E. Ferrell, Bahman Sepehrnia, Genetic studies of human apolipoproteins. II. A rapid one‐dimensional isoelectric focusing technique to characterize apolipoproteins A‐I, A‐II, A‐IV and C‐II of unfractionated plasma Electrophoresis. ,vol. 8, pp. 355- 358 ,(1987) , 10.1002/ELPS.1150080805