Passive smoking and risk of pulmonary tuberculosis in children immediately following infection. A case-control study.

摘要: Abstract Setting: Passive smoking-related respiratory disorders in children. Objectives: To assess the effect of passive smoking on development active pulmonary tuberculosis (PTB) children immediately following infection by Mycobacterium within family. Design: An unmatched case-control study which 93 contacts who became cases (active PTB diagnosed) and 95 did not (tuberculin-positive without evidence disease) were included. All household a new case bacillary tuberculosis. Smoking habits investigated questionnaire. Urinary cotinine was analysed. Odds Ratio (OR) adjusted for age socio-economic status using multiple logistic regression analysis. Results: risk factor (OR: 5.29; 95% confidence interval (CI): 2.33–12.82; P Conclusions: exposure to tobacco smoke associated with an increased developing infection. This is association great concern requiring health education programmes antitobacco medical advice.