Hookworm and poverty.

作者: Peter Hotez

DOI: 10.1196/ANNALS.1425.000

关键词:

摘要: Human hookworm infection is the leading cause of anemia and undernutrition second most important parasitic humans. Hookworm occurs almost exclusively in setting rural poverty developing countries tropics. The dependency reflects precise soil temperature requirements environmental life history stages parasite, whereas relationship between based on multiple factors, including inadequate sanitation, absence concrete floors home dwellings, lack access to essential medicines. Also, not only but also promotes because its health educational effects children, adverse effect pregnancy outcome, worker productivity. Since middle 20th century, reduction urbanization have successfully reduced prevalence world's industrialized nations some middle-income countries. However, control low-income still relies heavily frequent periodic use anthelminthic drugs either through deworming programs targeting school-aged children or integrated that simultaneously target seven neglected tropical diseases, hookworm. high rates reinfection possible emergence drug resistance will ultimately require development new tools—including Vaccine, one several so-called antipoverty vaccines could undergo testing over next decade.

参考文章(42)
Xue Haichou, Ren Hainan, P. J. Hotez, J. M. Hawdon, Feng Zheng, Zhan Bin, Xiao Shuhua, Wu Zhongxing, Sun Fenghua, Cao Hangqun, Qian Yixing, Epidemiology of human intestinal nematode infections in Wujiang and Pizhou counties, Jiangsu Province, China. Southeast Asian Journal of Tropical Medicine and Public Health. ,vol. 29, pp. 605- 610 ,(1998)
Simon Brooker, Jeffrey Bethony, Peter J. Hotez, Human Hookworm Infection in the 21st Century Advances in Parasitology. ,vol. 58, pp. 197- 288 ,(2004) , 10.1016/S0065-308X(04)58004-1
Lorenzo Savioli, Dirk Engels, Hiroyoshi Endo, Extending the benefits of deworming for development. The Lancet. ,vol. 365, pp. 1520- 1521 ,(2005) , 10.1016/S0140-6736(05)66433-1
Peter J Hotez, David H Molyneux, Alan Fenwick, Jacob Kumaresan, Sonia Ehrlich Sachs, Jeffrey D Sachs, Lorenzo Savioli, None, Control of Neglected Tropical Diseases The New England Journal of Medicine. ,vol. 357, pp. 1018- 1027 ,(2007) , 10.1056/NEJMRA064142
M. L. H. Mabaso, C. C. Appleton, J. C. Hughes, E. Gouws, The effect of soil type and climate on hookworm (Necator americanus) distribution in KwaZulu-Natal, South Africa. Tropical Medicine & International Health. ,vol. 8, pp. 722- 727 ,(2003) , 10.1046/J.1365-3156.2003.01086.X
Peter J Hotez, David H Molyneux, Alan Fenwick, Eric Ottesen, Sonia Ehrlich Sachs, Jeffrey D Sachs, Incorporating a Rapid-Impact Package for Neglected Tropical Diseases with Programs for HIV/AIDS, Tuberculosis, and Malaria PLOS Medicine. ,vol. 3, pp. 576- 584 ,(2006) , 10.1371/JOURNAL.PMED.0030102
Peter J. Hotez, Jeff Bethony, Maria Elena Bottazzi, Simon Brooker, David Diemert, Alex Loukas, New technologies for the control of human hookworm infection Trends in Parasitology. ,vol. 22, pp. 327- 331 ,(2006) , 10.1016/J.PT.2006.05.004