Development of neurocognitive disorders in HIV/AIDS

摘要: Correspondence: Brandon C Dennis Department of Neurology, University Kentucky College Medicine, 740 S Limestone St, Ste L-445, Lexington, KY 40536-0284, USA Tel +1 859 218 5051 Fax 323 3753 email brandoncdennis@uky.edu Abstract: The introduction highly active antiretroviral therapy has had an enormous impact on the management human immunodeficiency virus (HIV) infection and led to increase in survival decrease HIV-associated dementia. However, minor neurocognitive disturbances across various domains remain common 50% or more HIV patients according recent estimates. Increased longevity investigation several moderating complicating factors, including vascular disease, neurotoxicity, aging, substance abuse, hepatitis coinfection, psychiatric illness. This article provides a review history disorders (HAND), revised diagnostic terminology, factors development HAND, assessment techniques profiles, current treatment limitations, future research directions.