Produção de metabólitos bioativos pelo líquen Cladonia substellata Vainio

摘要: ABSTRACT – (Production of bioactive metabolites from lichen Cladonia substellata Vainio). This work purposed to make a comparisonbetween antimicrobial activity crude extracts , collected at Minas Gerais and Para States, Brazil, using thediffusion solid medium methods. Ether, chloroform, acetone extracts, 1 mg/mL, 0.1 0.01 were tested againsthuman pathogens phytopathogens. The submitted thin layer chromatography their active p rinciplesattributed by biochromatography. results demonstrated that the seven fungi species no sensitive C. Para. On other hand, four these microorganisms inhibited Gerais.All same bacteria species, but samples showed highest activity. Among inh ibitedbacteria Staphylococcus aureus was less sensitive, with an opposite behavior phytopathogen ones, highestsensitivity. Chromatographic assays revealed presence usnic acid in all thus most content samples. Thebiochromatograms reveals as principle synergic action norstictic found Geraissamples, what justify its