A one-step synthesis of pseudoephedrine glycinamide, a versatile precursor for the synthesis of α-amino acids
作者： Andrew G Myers , Taeyoung Yoon , James L Gleason
DOI: 10.1016/0040-4039(95)00820-3
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摘要: Abstract Both enantiomers of pseudoephedrine glycinamide [(+)- or (−)- 1 ] were synthesized by either two procedures: (1) a standard two-step coupling N -Boc-Gly with followed deprotection, (2) more economical one-step reaction Gly-OMe mediated LiCl and base.
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